陈鑫导师简介

个人简历：

陈鑫，男，汉族，副教授，基础医学院副院长，硕士研究生导师。2017年毕业于中国科学院大学，取得博士学位。主持国家自然科学基金、江西省自然科学基金、赣州市重点实验室建设等项目9项。以第一作者或通讯作者发表学术论文23篇，其中SCI收录论文20篇。

研究方向：

HIV分子流行病学、病毒变异与耐药。

科研课题：

[1]      国家自然科学基金地区基金项目，32460043，HIV优势重组位点的筛选及其增强病毒感染和复制能力的机制研究，2025.1-2028.12，32万，项目负责人。

[2]      国家自然科学基金青年基金项目，81902106，中缅边境新HIV-1重组型CRF83_cpx传播和流行的进化生物学研究，2020.1-2022.12，21万，项目负责人。

[3]      江西省自然科学基金面上项目，20242BAB25538，HIV获得性耐药患者病毒储存库中完整前病毒的演变规律研究，2024.6-2027.5，10万，项目负责人。

[4]       江西省自然科学基金青年基金项目，20202BABL216083，赣州市男男同性性行为人群HIV分子流行病学研究，2020.1-2021.12，6万，项目负责人。

[5]      赣南医学院高层次引进人才科研启动基金，QD201806，河南省医院病人HCV和HIV-1分子流行病学研究，2019.1-2023.12，60万，项目负责人。

[6]      赣南医学院特色创新团队项目，TS202001，病原生物进化与药物研发，2021.1-2023.12，10万，项目负责人。

[7]      赣州市重点实验室组建计划，赣市科发〔2020〕64号，赣州市病原生物进化与药物研究重点实验室，2021.1-2022.12，自筹，项目负责人。

[8]      赣州市“苏区之光”人才计划，赣市才字〔2021〕1号，科技创新人才培养专项，2022.1.-2023.12，15万，项目负责人。

[9]      江西省卫生健康委科技计划，SKJP_220210624，赣州市HIV-1分子流行病学特征及溯源研究，2022.1-2024.12，自筹，项目负责人。

发表论文：

[1] Wu Ya-Lan, Lan Gong-Wang, Jiang Lin-Ying, Chen Xin^*. HIV Reservoirs Across Multiple Tissues: From Heterogeneous Mechanisms to Therapeutic Targeting [J]. Microorganisms. 2026;14(4):844.

[2]      Xie Ying-Na^#, Li Zheng-Xu^#, Chen Ya-Ting, Li Yong-Juan, Yang Zhu-Qian, Ren Yuan, Yang Zi-Xuan, Chen Xin^*. Genetic diversity of HIV in Yunnan, China: the role of second-generation recombination involving circulating and unique recombinant forms [J]. Virology Journal. 2025;22(1):240.

[3]      Huang Dan-Dan^#, Liu Jun-Jie^#, Chen Ya-Ting, Yang Rong-Rong, Su Jun-Zhi, Gao Qian, Chen Xin^*. Characteristics of primary drug resistance in newly diagnosed HIV-infected individuals in Ganzhou, China [J]. AIDS Research and Therapy. 2025;22(1): 63.

[4]      Zhang Xiao-Yi^#, Cao Hong-Min^#, Chen Ya-Ying, Lian Chao-Xian, Zeng Ting, Liu Jun-Jie, Su Jun-Zhi, Gao Qian, Zhu Feng-Xiu, Zhang Yu-Ning, Huang Dan-Dan, Zhou Yan-Heng, Chen Xin^*. Characterization of a novel HIV-1 second-generation circulating recombinant form (CRF144_07C) in Ganzhou, China [J]. Genes & Diseases. 2025;14(4): 101443.

[5]      Zeng Ting, Lian Chao-Xian, Zhang Xiao-Yi, Liu Ping-Qing, Ao Jian, Zhou Gang-Feng, Chen Xiao-Dong, Huang Dan-Dan, Hu Dian-Gui^*, Chen Xin^*. Clinical symptoms and molecular epidemiologic characteristics of varicella patients among children and adults in Ganzhou, China [J]. Virology Journal. 2025;22(1):44.

[6]      Zeng Ting^#, Chen Xin^#, Zhang Xiao-Yi, Lian Chao-Xian, Yang Rong-Rong, Yu Li-Ling, Liao Xiao-Kang, Huang Dan-Dan, Zhang Yu-Ning, Cao Hong-Min^*. Outcomes of antiretroviral treatment for 0-14-year-old children living with HIV in Ganzhou, China, 2006-2023 [J]. AIDS Research and Therapy. 2024; 21(1): 8.

[7]      谢莹娜, 程思维, 陈鑫^*. 江西省HIV-1流行现状,治疗与耐药的研究进展[J]. 赣南医学院学报, 2023, 43(02): 182-187.

[8]      Xie Ying-Na^#, Zhu Feng-Xiu^#, Zhong You-Tian, Chen Ya-Ting, Gao Qian, Lai Xiao-Ling, Liu Jun-Jie, Huang Dan-Dan, Zhang Yu-Ning, Chen Xin^*. Distribution characteristics of drug resistance mutations of HIV CRF01_AE, CRF07_BC and CRF08_BC from patients under ART in Ganzhou, China [J]. Journal of Antimicrobial Chemotherapy, 2021, 76(11): 2975-2982.

[9]      Xie Ying-Na, Zhang Yu-Ning, Cheng Si-Wei, Huang Dan-Dan, Xie Bing-Yu, Huang Zhen, Zhou Yan-Heng, Zhu Da-Qing^*, Chen Xin^*. The Genetic Diversity of HIV-1 Within Antiretroviral-Naive Outpatients in Ganzhou, China [J]. AIDS Research and Human Retroviruses, 2021, 37(2): 147-150.

[10]      Xie Ying-Na^#, Li Si-Le^#, Yang Rong-Rong, Huang Jin, Peng Xia, Xu Wen, Cheng Si-Wei, Zhou Yan-Heng, Chen Xin^*, Li Hong^*. Genetic Characteristics of Three Unique Recombinant Forms of HIV-1 in Yunnan, China [J]. AIDS Research and Guman Retroviruses, 2021, 37(7): 580-584.

[11]      Wang Yu^#, Chen Xin^#, Ye Mei, Pang Wei, Zhang Chiyu, Xiong Si-Dong^*, Zheng Yong-Tang^*. Consistency of spatial dynamics of HIV-1 and HCV among HIV-1/HCV coinfected drug users in China [J]. BMC Infectious Diseases, 2021, 21(1): 1001.

[12]      Li Yingxue^#, Chen Xin^#, Zhao Yongjuan^#, Wan Zhenzhou, Zeng Yi, Ma Yingying, Zhou Lianqun, Xu Gaolian, Reboud Julien, Cooper Jonathan M^*, Zhang Chiyu^*. A rapid variant-tolerant reverse transcription loop-mediated isothermal amplification assay for the point of care detection of HIV-1 [J]. Analyst, 2021, 146(17): 5347-5356.

[13]      Chen Ya-Ting^#, Li Zheng-Xu^#, Xie Ying-Na, Zhao Lei, Hu An-Yan, An Li, Dong Xian-Ya, Liu Dong-Xu, Ma Qiang^*, Chen Xin^*. Genetic Characterization of a Novel HIV-1 Second-Generation Recombinant Form Originating from CRF86_BC and a Unique Recombinant Form in Yunnan, China [J]. AIDS Research and Human Retroviruses, 2021, 37(12): 985-989.

[14]      谢莹娜, 黄真, 黄丹丹, 张宇宁, 陈鑫^*. 赣州市新型冠状病毒SARS-CoV-2传播网络分析 [J]. 赣南医学院学报, 2020, 40(02): 124-128.

[15]      Ouyang Song-Mao, Zhu Hong-Quan, Xie Ying-Na, Zou Zhi-Sheng, Zuo Hui-Min, Rao Yun-Wei, Liu Xiao-Yan, Zhong Bin, Chen Xin^*. Temporal changes in laboratory markers of survivors and non-survivors of adult inpatients with COVID-19 [J]. BMC Infectious Diseases, 2020, 20(1): 952.

[16]      Chen Xin, Ye Mei, Wang Yu, Zhang Chiyu^*, Zheng Yong-Tang^*. Laos is Affected by HIV CRF01_AE and the Newly Identified CRF97_01B [J]. Virologica Sinica, 2020, 35(5): 538-547.

[17]      Chen Xin, Zhou Yan-Heng, Ye Mei, Wang Yu, Duo Lin, Pang Wei, Zhang Chiyu^*, Zheng Yong-Tang^*. Burmese injecting drug users in Yunnan play a pivotal role in the cross-border transmission of HIV-1 in the China-Myanmar border region [J]. Virulence, 2018, 9(1): 1195-1204.

[18]      Chen Xin, Duo Lin, Ye Mei, Zhang Chiyu^*, Zheng Yong-Tang^*. Non-Chinese Immigrants: Challenge Faced by Yunnan of China to Achieve the 90-90-90 Goals [J]. Virologica Sinica, 2018, 33(3): 291-293.

[19]      Chen Xin, Ye Mei, Pang Wei, Smith Davey M, Zhang Chiyu^*, Zheng Yong-Tang^*. First Appearance of HIV-1 CRF07_BC and CRF08_BC Outside China [J]. AIDS Research and Human Retroviruses, 2017, 33(1): 74-76.

[20]      Chen Xin, Ye Mei, Duo Lin, Pang Wei, Smith Davey M, Zhang Chiyu^*, Zheng Yong-Tang^*. First description of two new HIV-1 recombinant forms CRF82_cpx and CRF83_cpx among drug users in Northern Myanmar [J]. Virulence, 2017, 8(5): 497-503.

[21]      Chen Xin, Zhu Lin, Zhou Yan-Heng, Liu Feng-Liang, Li Hong, Yao Zhi-Hong, Duo Lin, Pang Wei, Ye Mei, Zheng Yong-Tang^*. Factors associated with needle sharing among people who inject drugs in Yunnan, China: a combined network and regression analysis [J]. Infectious Diseases of Poverty, 2016, 5(1): 73.

[22]      Chen Xin^#, Ye Mei^#, Zhou Yan-Heng, Liu Feng-Liang, Duo Lin, Li Hong, Pang Wei, Zheng Yong-Tang^*. High seroprevalence of toxoplasma gondii and HIV-1 co-infection among drug users in Yunnan province, southwest China [J]. Science China Life Sciences, 2016, 59(8): 857-859.

[23]      陈鑫, 庞伟, 周衍衡, 郑永唐^*. 澜沧江-湄公河次区域HIV-1分子流行病学及跨境传播研究进展 [J]. 中国国境卫生检疫杂志, 2014, 37(01): 63-67,72.

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