路尧导师简介

路尧，男，实验师，硕士生导师，2024 年毕业于兰州大 学医学院，获得病理学与病理生理学博士学位。研究方向为 肿瘤学，主要研究乳腺癌和胃癌的发生发展机制，近 5 年以 第一作者或通讯作者发表高水平 SCI 论文 9 篇。指导学生参 加“全国大学生基础医学创新论坛实验设计大赛”获全国铜奖 1 项，指导大学生创新创业训练国家级项目立项 2 项。

欢迎感兴趣的同学联系！

电话：18329101510                                         Email:luy@gmu.edu.cn

以第一作者或通讯作者发表的代表性论文：

(1)   Lu Yao;   Song Tao;  Xue Xue;   Cao  Gaolu; Huang  Panpan*.   Kinesin superfamily  proteins: roles   in

osteosarcoma. Frontiers in Bioscience-Landmark, 2021, 26(8): 370-378.

(2)   Lu Yao;  Cao  Gaolu; Lan Haiying; Liao Hua; Hu Yaqiong; Feng Haihua; Liu, Xiaojian; Huang Panpan*.

Chondrocyte-derived Exosomal miR-195 Inhibits Osteosarcoma  Cell Proliferation and Anti-Apoptotic by Targeting KIF4A in vitro and in vivo. Translational Oncology, 2021, 16: 101289.

(3)   Liu     Wenyu;     Li    Jing;     Zhao     Rui;     Lu    Yao;     Huang     Panpan*.     The    Uridine     diphosphate (UDP)-glycosyltransferases  (UGTs)  superfamily:  the  role  in  tumor  cell  metabolism.  Front  Oncol,  2023, 12:1088458.

(4)   Zeng X, Lu Y, Zeng T, Liu W, Huang W, Yu T, Tang X, Huang P, Li B, Wei H. RNA demethylase FTO participates in malignant progression of gastric cancer by regulating SP1-AURKB-ATM pathway. Commun Biol. 2024 Jul 2;7(1):800.

(5)   Lu Yao#; Huang Panpan#; Li Yanli; Liu Wenyu; Li Jing; Zhao Rui; Feng Haihua;  Shi Ce; Cao Gaolu. The FBXO32/ATR/ATM  axis  acts  as  a  molecular  switch  to  control  the  sensitivity  of osteosarcoma  cells  to irradiation through its regulation of EXO1 expression. Acta Biochim Biophys Sin, 2023, 55(5):842-852.

(6)   Yao Lu#; Panpan Huang#; Xueliang Zeng; Wenyu Liu; Rui Zhao; Jing Li; Gaolu Cao; Yaqiong Hu; Qiuxiang  Xiao;    Meng    Wu;     Weicai    Huang;    Xuerui     Tang;    Xiaojian     Liu;    Hulai    Wei.     Inhibition    of  FNDC1 suppresses gastric cancer progression by interfering with Gβγ-VEGFR2 complex formation. iScience, 2023, 26(9):107534.

(7)   Huang Weicai, Liu Wenyu, Yu Tingting, Zhang Zhaoyang, Zhai Lingyun, Huang Panpan*, Lu Yao*. Effect of  anti-COVID-19   drugs   on patients with cancer. European  journal   of  medicinal   chemistry,   2024, 15;268:116214.

(8)   Wang Yuxuan, Liu Zhiwei, Lv Yulu, Long Jiayang, Lu Yao, Huang Panan*. Mechanisms of radioresistance and radiosensitization strategies for Triple Negative Breast Cancer. Translational oncology, 2025, 55:102351.

(9)   Zhang Yilei, Xie Yuhuan, Wang Yiwen, Huang Panpanv*, Lu Yao*. The Role of Radiosensitizing Drugs in Osteosarcoma Treatment: Mechanisms and Clinical Perspectives. Drug design, development and therapy, 2025;19:1927-1942.