张海生导师简介

       张海生，博士，讲师。2025年毕业于中山大学，获博士学位，同年入职赣南医科大学基础医学院。目前主要研究RNA修饰在肿瘤中的作用及其靶向治疗策略。作为项目主持人主持赣南医科大学高层次人才启动项目、江西省职业早期青年科技人才培养项目和国家自然科学基金青年科学基金（C类）等课题。以第一（含共同）作者身份在Cancer Research，Acta Pharmaceutica Sinica B，Journal of Biomedical Science和Advanced Science等高水平中科院一区期刊发表论文4篇。

代表性论文：

(1) Zhang HS#, Zhou JW#, Li JX#, Wang ZT#, Chen ZJ, Lv ZY, Ge LC, Xie GY, Deng GM, Rui YL, Huang HB, Chen LK*, Wang HS*. N6-Methyladenosine Promotes Translation of VEGFA to Accelerate Angiogenesis in Lung Cancer. 2023, Cancer Research.

(2) Zhang HS#, Lu LL#, Yi C#, Jiang T#, Lu YQ, Yang XY, Zhong K, Zhou JW, Li JX, Xie GY, Chen ZJ, Jiang ZP, Asadikaram G, Peng YX*, Zhou D*, Wang HS*. BRD4 regulates m6A of ESPL1 mRNA via interaction with ALKBH5 to modulate breast cancer progression. 2025, Acta Pharmaceutica Sinica B.

(3) Zhang HS#, Yi C#, Li JN, Lu YQ, Wang HR, Tao LJ, Zhou JW, Tan YH, Li JX, Chen ZJ, Asadikaram G, Cao J, Peng JX, Li WL*, He JM*, Wang HS*. N6-methyladenosine RNA modification regulates the transcription of SLC7A11 to modulate ferroptosis. 2025, Journal of Biomedical Science.

(4) Rui YL#, Zhang HS#, Yu KN, Qiao SY, Gao CL, Wang XS, Yang WF, Asadikaram G, Li ZG, Zhang K, Peng JX, Li JX*, He JM*, Wang HS*. N6-Methyladenosine Regulates Cilia Elongation in Cancer Cells by Modulating HDAC6 Expression. 2025, Advanced Science.

课题组地址：赣南医科大学蓉江校区科技大楼

电话：15270871325

邮箱：zhanghaisheng@gmu.cn